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Wellness · Vitamins & Minerals ·B12+D3

B12+D3

B12+D3

180 Vegan Capsules · Methylcobalamin · Vitashine™ D3 · L-5-MTHF Folate · 100% Indian RDA

Evidence: High Active-Form B12 + Folate Vegan-Suitable Daily Foundation

This is for you if

  • You're vegan or vegetarian — B12 is almost entirely absent from plant foods
  • You spend most of your day indoors, regardless of where you live in India
  • You're over 50 — stomach acid declines with age, reducing B12 absorption from food
  • You want active forms (methylcobalamin and L-5-MTHF) rather than the cheaper cyanocobalamin and folic acid most multivitamins use

What changes, and when

  • Wk 2–4 Daily energy baseline if you were B12-deficient
  • Wk 6–8 Vitamin B12 & D3 levels improve
  • Wk 12+ Folate-dependent processes (methylation, neural function) reach steady state
  • 6+ months The dose is right; the form is right; the work is done quietly in the background

Key Actives per Serving (1 Capsule)

  • Vitamin D3 Vitashine™ Cholecalciferol from lichen 600 IU (100% RDA)
  • Vitamin B9 (Folate) L-5-Methyltetrahydrofolate (L-5-MTHF) 300mcg DFE (100% RDA)
  • Vitamin B12 Methylcobalamin 2.2mcg (100% RDA)
  • Capsule shell Hypromellose (HPMC) — Plant-derived, Vegan Zero fillers

Key clinical outcomes supported

  • Correction and maintenance of B12 status
  • Vitamin D sufficiency in low-sun-exposure adults
  • Methylation pathway function and homocysteine regulation
  • Vegan-suitable B12 supplementation without animal-derived sources
  • Maintenance of cognitive and neural function with consistent daily intake
Regular price ₹900.00
Regular price MRP Sale price ₹900.00
/ 180 Capsule · ₹5 per serving
Taxes included.
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01

Ingredients & Supplement Facts

Ingredient & Form Dose Rationale
Methylcobalamin Methylcobalamin 2.2mcg

Kira et al. 1994: improved nerve conduction in diabetic neuropathy at 1500 mcg/day. Zhang et al. 2013: comparable efficacy to cyanocobalamin without cyanide moiety.

L-Methyltetrahydrofolate Vitamin D3 600IU

Pietrzik et al. 2010: comparable plasma folate response to folic acid without unmetabolised folic acid accumulation. Obeid et al. 2013: preferred form in MTHFR C677T variants.

Vitamin D3 100,000 IU/g Powder L-5-MTHF 300mcg DFE

Tripkovic et al. 2012 meta-analysis: D3 raises 25(OH)D more effectively than D2. Heaney et al. 2003: oral D3 absorption equivalent across powder and oil matrices when bioequivalent doses given.

02

Dosage & Rationale

1
Capsule
1 Capsule daily · with food · morning or with lunch

Why with food? — Vitamin D3 is fat-soluble — absorbed significantly better when taken with a meal containing dietary fat. Morning or lunch dosing is preferred over evening because the small B-vitamin content can affect sleep onset in sensitive adults.

Why one capsule daily, not split doses? — B12 and D3 have long enough half-lives in the body that once-daily dosing is sufficient for maintenance. Folate's effect on methylation is a daily process; consistent daily intake matters more than timing precision.

Loading Period: 6–8 weeks for blood markers to reflect supplementation

If you're starting from a documented deficit (low serum B12, low 25-OH Vitamin D, or both), the maintenance dose at 100% RDA may not be sufficient on its own to correct the deficit — it's calibrated to maintain normal status, not to aggressively replete a depleted state. Consult your physician about a corrective protocol if your levels are well below the normal range.

03

Batch & Quality Details

Batch Number
Manufactured
Expiry
Status ● Archived
04

Third-Party Testing — Batch

05

Safety & Competition Notes

  • No WADA Prohibited Substances
  • Vegan (HPMC capsule shell)
  • Free from soy, dairy, sugar, nuts, gluten, artificial colours, fillers, preservatives

Pregnancy: Folate is critical for foetal neural development; consult your gynaecologist for the right total daily folate intake during pregnancy. This product contributes 300mcg DFE of active folate — your physician may recommend additional folate during the first trimester.
Prescription medication interactions: Methotrexate (used for cancer and autoimmune conditions) interacts with folate — consult your physician. Metformin (diabetes) can reduce B12 absorption; supplementation is often beneficial but doses should be reviewed.
Already taking a multivitamin? Most multivitamins contain B12 and D3 at lower doses with the cheaper forms (cyanocobalamin and folic acid). Taking this product alongside a standard multivitamin is generally safe, but the active forms in this product may make the multivitamin's B12 and folate redundant. Read both labels and decide which to keep.
MTHFR gene variant: Adults with documented MTHFR C677T or A1298C variants benefit specifically from L-5-MTHF (active folate) over folic acid. This product is the better choice if you have a confirmed variant.
Vegan and vegetarian readers: This is the right product for you. B12 in plant foods is essentially absent — supplementation is not optional for long-term vegan health. D3 from sun exposure is unreliable for indoor lifestyles regardless of latitude.

06

Evidence Dossier

Overall Evidence Grade HIGH · B12 + D3 Foundational Nutrients

The two most commonly deficient vitamins in adult populations. Both have extensive evidence for status restoration through supplementation.

Ingredient Mechanism Evidence Key Notes
Methylcobalamin Direct cofactor for methionine synthase; supports homocysteine metabolism, DNA methylation, and myelin synthesis ● High
L-Methyltetrahydrofolate Bypasses MTHFR enzyme conversion required by synthetic folic acid; supports homocysteine clearance, DNA methylation, and neural tube development ● High
Vitamin D3 100,000 IU/g Powder Hormone precursor activated to 1,25-dihydroxyvitamin D; regulates calcium and phosphate homeostasis, immune modulation, and gene transcription ● High
07

What Each Ingredient Does

01 · Methylcobalamin

Cholecalciferol — The sunshine vitamin, vegan-sourced

Cholecalciferol supports calcium absorption, immune function, muscle function, and mood regulation. The 600 IU dose matches Indian RDA for daily maintenance. Vitashine™ sources it from lichen rather than lanolin — molecularly identical to standard D3, fully vegan, addressing the 70–90% deficiency rate in urban Indian adults.

02 · L-Methyltetrahydrofolate

L-5-MTHF — Active folate, ready-to-use

L-5-Methyltetrahydrofolate is the bioactive form of folate the body uses directly, bypassing the MTHFR enzyme conversion required by synthetic folic acid. The 300 mcg DFE dose supports methylation, homocysteine regulation, and red blood cell formation — clinically meaningful regardless of MTHFR genotype.

03 · Vitamin D3 100,000 IU/g Powder

Methylcobalamin — The bioactive form of B12

Methylcobalamin is the form B12 takes when the body actually uses it — supporting neural function, red blood cell formation, and energy metabolism. The 2.2 mcg dose meets Indian RDA. Crosses the blood-brain barrier more readily than cyanocobalamin, and avoids the conversion step that limits older adults.

08

Frequently Asked Questions

09

Verified Reviews

PRODUCT QUESTIONS

Have a clinical, formulation, or dosing question that the page does not answer? Write to wecare@unived.com.

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