Vitamin C

Vitamin C is a powerful nutrient that provides significant
health benefits. Best known for boosting immune function and collagen
production, it also supports overall wellness, energy levels, and vitality [2].
As humans cannot produce vitamin C endogenously, external sources through diet
or supplements are necessary.

There are many vitamin C products available to increase
levels in the body. Most contain ascorbic acid, the synthetic form of vitamin C
primarily derived from genetically modified corn. Ascorbic acid is the cheapest
option. However, it is synthetically produced in laboratories and differs from
natural vitamin C. Specifically, ascorbic acid is missing certain cofactors
like rutin, bioflavonoids, factor K, factor J, factor P, tyrosinase, and
ascorbinogen that contribute to the beneficial effects of natural vitamin C.

In contrast, vitamin C from natural sources like Amla fruit
contain the vitamin in its original form alongside supportive cofactors and
nutrients. This makes natural vitamin C fully bioavailable and biologically
active compared to synthetic versions, which have poor activity levels due to
absent cofactors. Studies also show natural vitamin C with bioflavonoids
absorbs better than ascorbic acid alone. Additionally, natural vitamin C is
gradually absorbed versus synthetic vitamin C [1].

In summary, natural vitamin C provides optimal health
benefits due to the supportive network of cofactors absent from synthetic
ascorbic acid. Those seeking to increase vitamin C levels through diet or
supplements should consider options containing vitamin C in its whole, natural
form.

Our Formulation

Unived Vitamin C has plant-based Vitamin C, derived from
Amla and contains Citrus Bioflavonoids. Each serving of 80mg of natural Vitamin
C meeting 100% RDA and 84mg Hesperidin (citrus bioflavonoids).

Mode of action:

• Vitamin C: Vitamin C deficiency results in impaired and
  higher susceptibility to infections.
• It contributes to immune defense by supporting various
  cellular functions of both the innate and adpative immune system [2] [3].
• Vitamin C enhances the differentiation and proliferation of
  immune cells, likely due to its gene regulating effects [5].
• Stimulates production, function and movement of certain
  immune cells such as leukocytes, lymphocytes, neutrophils and phagocytes [4,
  5].
• Has a role in antimicrobial and Natural Killer cell (NK
  cell) activities.
• Can increase serum levels of antibodies.

References:

1. Vinson, Joe A., and Pratima Bose. "Comparative
bioavailability to humans of ascorbic acid alone or in a citrus extract."
The American journal of clinical nutrition 48.3 (1988): 601-604.

2. Deruelle, Fabien, and Bertrand Baron. "Vitamin C: is
supplementation necessary for optimal health?." The Journal of Alternative
and Complementary Medicine 14.10 (2008): 1291-1298.

3. Carr, Anitra C., and Silvia Maggini. "Vitamin C and
immune function." Nutrients 9.11 (2017): 1211.

4. Wintergerst, Eva S., Silvia Maggini, and Dietrich H.
Hornig. "Immune-enhancing role of vitamin C and zinc and effect on
clinical conditions." Annals of Nutrition and Metabolism 50.2 (2006):
85-94.

5. Johnston, Carol S., Gillean M. Barkyoumb, and Sara S.
Schumacher. "Vitamin C supplementation slightly improves physical activity
levels and reduces cold incidence in men with marginal vitamin C status: A
randomized controlled trial." Nutrients 6.7 (2014): 2572-2583.

6. Grosso, Giuseppe, et al. "Effects of vitamin C on
health: a review of evidence." Front Biosci (Landmark Ed) 18.3 (2013):
1017-1029.

7. Assini, Julia M., Erin E. Mulvihill, and Murray W. Huff.
"Citrus flavonoids and lipid metabolism." Current opinion in
lipidology 24.1 (2013): 34-40.

8. Banjarnahor, Sofna DS, and Nina Artanti.
"Antioxidant properties of flavonoids." Medical Journal of Indonesia
23.4 (2014): 239-44.¬

9. Gul, Maryam, et al. "Functional and nutraceutical
significance of Amla (Phyllanthus emblica L.): a review." Antioxidants
11.5 (2022): 816.