Magnesium Glycinate Chelate Buffered

Magnesium Glycinate Chelated Buffered

Magnesium is a vital mineral that regulates over 300 enzymatic reactions in the human body. It supports neuromuscular function, cardiovascular rhythm, bone metabolism, and mitochondrial energy production. Magnesium deficiency, though common, often goes unnoticed and may manifest as digestive issues, muscle cramps, anxiety, and poor sleep.¹ ²

Chelated for High Absorption

We use Magnesium Glycinate Chelate, a form in which magnesium is bound to the amino acid glycine. This chelation protects magnesium from interacting with other compounds in the digestive tract, significantly improving its absorption and bioavailability over forms like magnesium oxide or citrate.³ Glycine additionally supports relaxation and better sleep quality.⁴

Buffered for Higher Elemental Magnesium

Pure Magnesium Glycinate Chelate provides approximately 14.1% elemental magnesium by weight.

To increase the elemental magnesium content per dose while maintaining high bioavailability and gastrointestinal tolerance, the chelate is buffered with magnesium oxide, resulting in a Chelated Buffered blend that delivers 22% elemental magnesium. This allows for higher potency without compromising absorption or causing laxative effects.

Neurological and Psychological Support

Magnesium plays a key role in neurotransmitter modulation and brain function. Clinical data links adequate magnesium intake to reduced symptoms of depression and anxiety, improved mood, and enhanced cognitive clarity.⁵

Magnesium Glycinate Chelate vs Buffered Chelate

• Magnesium Bisglycinate Chelate (standard chelate) contains ~14.1% elemental magnesium by weight.
• In its pure chelated form, it is made by fully reacting magnesium with two molecules of the amino acid glycine.

However, when a product claims ~20–22% elemental magnesium, it usually means:

• It has been buffered, meaning a portion of magnesium oxide has been blended with the chelate. This increases the elemental magnesium percentage without increasing the chelation ratio.
• The final product is a mixture of magnesium bisglycinate chelate + magnesium oxide, referred to as "magnesium glycinate buffered" or "chelated buffered".

So, buffering does not enhance the chelation effect. It is a manufacturing technique to Increase elemental magnesium per gram of powder and Maintain decent absorption (better than oxide alone, but lower than fully chelated magnesium glycinate).

References:

1. Schwalfenberg & Genuis. Scientifica. 2017; 4179326.
2. Swaminathan R. Clin Biochem Rev. 2003; 24(2):47–66.
3. Albion Minerals Technical Dossier – Magnesium Glycinate Chelate.
4. Kawai N et al. Neuropsychopharmacology. 2015; 40(6):1405–1416.
5. Eby GA & Eby KL. Med Hypotheses. 2006; 67(2):362–370.